The following polygenic scores are included in HRS Polygenic Score Data (PGS).
| Phenotype of GWAS meta-analysis | GWAS meta-analysis citation | Release 1 (May 2017) | Release 2 (April 2018) | Release 3 (Oct 2018) | Release 4 (Feb 2020) |
|---|---|---|---|---|---|
| Educational Attainment 2* | Okbay (SSGAC, 2016) | 2006-2012 | 2006-2012 | 2006-2012 | |
| Height | Wood (GIANT, 2014) | 2006-2010 | 2006-2012 | 2006-2012 | 2006-2012 |
| Body Mass Index (BMI)** | Locke (GIANT, 2015) | 2006-2010 | 2006-2012 | 2006-2012 | 2006-2012 |
| Waist Circumference (WC) | Shungin (GIANT, 2015) | 2006-2010 | 2006-2012 | 2006-2012 | 2006-2012 |
| Waist-to-Hip Ratio (WHR) | Shungin (GIANT, 2015) | 2006-2010 | 2006-2012 | 2006-2012 | 2006-2012 |
| Diastolic Blood Pressure (DBP) | Ehret (ICBP, 2011) | 2006-2010 | |||
| Systolic Blood Pressure (SBP) | Ehret (ICBP, 2011) | 2006-2010 | |||
| Pulse Pressure (PP) | Wain (ICBP, 2011) | 2006-2010 | |||
| Mean Arterial Pressure (MAP) | Wain (ICBP, 2011) | 2006-2010 | |||
| Alzheimer's Disease (AD) | Lambert (IGAP, 2013) | 2006-2010 | 2006-2012 | 2006-2012 | 2006-2012 |
| General Cognition* | Davies (CHARGE, 2015) | 2006-2010 | 2006-2012 | 2006-2012 | 2006-2012 |
| Schizophrenia | Ripke (PGC, 2014) | 2006-2010 | 2006-2012 | 2006-2012 | 2006-2012 |
| Smoking Initiation (ever/never) | Furberg (TAG, 2010) | 2006-2010 | 2006-2012 | 2006-2012 | 2006-2012 |
| Subjective Wellbeing* | Okbay (SSGAC, 2016) | 2006-2010 | 2006-2012 | 2006-2012 | 2006-2012 |
| Neuroticism* | Okbay (SSGAC, 2016) | 2006-2010 | 2006-2012 | 2006-2012 | 2006-2012 |
| Depressive Symptoms* | Okbay (SSGAC, 2016) | 2006-2010 | 2006-2012 | 2006-2012 | 2006-2012 |
| Longevity* | Broer (CHARGE, 2015) | 2006-2012 | 2006-2012 | 2006-2012 | |
| Number of Cigarettes Smoked per Day (CPD) | Furberg (TAG, 2010) | 2006-2012 | 2006-2012 | 2006-2012 | |
| Coronary Artery Disease (CAD) | Schunkert (CARDIoGRAM, 2011) | 2006-2012 | 2006-2012 | 2006-2012 | |
| Myocardial Infarction (MI) | Nikpay (CARDIoGRAMplusC4D, 2015) | 2006-2012 | 2006-2012 | 2006-2012 | |
| Type II Diabetes (T2D) | Morris (DIAGRAM, 2012) | 2006-2012 | 2006-2012 | 2006-2012 | |
| Attention Deficit/Hyperactivity Disorder (ADHD) PGC 2010 | Neale (PGC, 2010) | 2006-2012 | 2006-2012 | 2006-2012 | |
| Attention Deficit/Hyperactivity Disorder (ADHD) PGC 2017 | Demontis (PGC, 2017) | 2006-2012 | 2006-2012 | 2006-2012 | |
| Autism | Anney (PGC, 2017) | 2006-2012 | 2006-2012 | 2006-2012 | |
| Bipolar Disorder (BIP) | Sklar (PGC, 2011) | 2006-2012 | 2006-2012 | 2006-2012 | |
| Mental health cross disorder | Smoller (PGC, 2013) | 2006-2012 | 2006-2012 | 2006-2012 | |
| Age at Menarche | Perry (ReproGen, 2014) | 2006-2012 | 2006-2012 | 2006-2012 | |
| Age at Menopause | Day (ReproGen, 2015) | 2006-2012 | 2006-2012 | 2006-2012 | |
| Plasma Cortisol | Bolton (CORNET, 2014) | 2006-2012 | 2006-2012 | 2006-2012 | |
| Major Depressive Disorder (MDD) | Ripke (PGC, 2013) | 2006-2012 | 2006-2012 | 2006-2012 | |
| Extraversion | van den Berg (GPC, 2016) | 2006-2012 | 2006-2012 | 2006-2012 | |
| Antisocial Behavior | Tielbeek (BROAD, 2017) | 2006-2012 | 2006-2012 | ||
| Educational Attainment 3* | Lee (SSGAC, 2018) | 2006-2012 | 2006-2012 | ||
| Obsessive Compulsive Disorder (OCD) | (IOCDF-GC and OCGAS, 2017) | 2006-2012 | 2006-2012 | ||
| Age at first birth (combined, female, male) | Barban (Sociogenome, 2016) | 2006-2012 | 2006-2012 | ||
| Number children ever born (combined, female, male) | Barban (Sociogenome, 2016) | 2006-2012 | 2006-2012 | ||
| Major Depressive Disorder 2 (MDD2) | Wray (PGC, 2018) | 2006-2012 | 2006-2012 | ||
| Post Traumatic Stress Disorder (PTSD: combined, European, African) | Duncan (PGC, 2018) | 2006-2012 | 2006-2012 | ||
| High Density Lipoprotein (HDL) | Willer (GLGC, 2013) | 2006-2012 | 2006-2012 | ||
| Low Density Lipoprotein (LDL) | Willer (GLGC, 2013) | 2006-2012 | 2006-2012 | ||
| Total Cholesterol (TC) | Willer (GLGC, 2013) | 2006-2012 | 2006-2012 | ||
| Anxiety (factor score, case-control) | Otowa (ANGST, 2016) | 2006-2012 | 2006-2012 | ||
| General Cognition 2* | Davies (CHARGE, 2018) | 2006-2012 | |||
| Blood urea nitrogen (BUN) - European ancestry GWAS | Wuttke (CKDGen, 2019) | 2006-2012 | |||
| Blood urea nitrogen (BUN) - transancestry GWAS | Wuttke (CKDGen, 2019) | 2006-2012 | |||
| Chronic kidney disease (CKD) - European ancestry GWAS | Wuttke (CKDGen, 2019) | 2006-2012 | |||
| Chronic kidney disease (CKD) - transancestry GWAS | Wuttke (CKDGen, 2019) | 2006-2012 | |||
| eGFR - European ancestry GWAS | Wuttke (CKDGen, 2019) | 2006-2012 | |||
| eGFR - transancestry GWAS | Wuttke (CKDGen, 2019) | 2006-2012 | |||
| Diastolic blood pressure (DBP)* | Liang (COGENT, 2017) | 2006-2012 | |||
| Hypertension (HTN)* | Liang (COGENT, 2017) | 2006-2012 | |||
| Pulse pressure (PP)* | Liang (COGENT, 2017) | 2006-2012 | |||
| Systolic blood pressure (SBP)* | Liang (COGENT, 2017) | 2006-2012 | |||
| Body Mass Index 2 (BMI2)** | Yengo (GIANT, 2018) | 2006-2012 | |||
| Height 2** | Yengo (GIANT, 2018) | 2006-2012 | |||
| Age at smoking initiation (AI)* | Liu (GSCAN, 2019) | 2006-2012 | |||
| Cigarettes per day (CPD)* | Liu (GSCAN, 2019) | 2006-2012 | |||
| Alcoholic drinks per week (DPW)* | Liu (GSCAN, 2019) | 2006-2012 | |||
| Smoking cessation (SC)* | Liu (GSCAN, 2019) | 2006-2012 | |||
| Smoking initiation (SI)* | Liu (GSCAN, 2019) | 2006-2012 | |||
| Lifetime cannabis use | Pasman (ICCUKB, 2019) | 2006-2012 | |||
| Alzheimer's disease - pT=1 with APOE/TOMM40 region | Kunkle (IGAP, 2019) | 2006-2012 | |||
| Alzheimer's disease - pT=1 without APOE/TOMM40 region | Kunkle (IGAP, 2019) | 2006-2012 | |||
| Alzheimer's disease - pT=0.01 with APOE/TOMM40 region | Kunkle (IGAP, 2019) | 2006-2012 | |||
| Alzheimer's disease - pT=0.01 without APOE/TOMM40 region | Kunkle (IGAP, 2019) | 2006-2012 | |||
| HbA1c - African ancestry GWAS | Wheeler (MAGIC, 2017) | 2006-2012 | |||
| HbA1c - European ancestry GWAS | Wheeler (MAGIC, 2017) | 2006-2012 | |||
| Alchol dependence - unrelated, European ancestry GWAS | Walters (PGC, 2018) | 2006-2012 | |||
| Educational Attainment 3* with 23andMe GWAS | Lee (SSGAC, 2018) | 2006-2012 |
*The GWAS Meta-analysis was re-analyzed without the HRS cohort to produce weights independent of the HRS contribution
**The GWAS Meta-analysis includes HRS and has not been re-run without the HRS
All other GWAS did not include HRS
References
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